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Filtered Search Results
Medchemexpress LLC 4-(4,5-diphenyl-1H-imidazol-2-yl)benzoic acid | 5496-35-5 | MFCD00999654 | 99.7% | 340.37 | C22H16N2O2 | 250 MG
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I-XW-053 is a small-molecule inhibitor of the HIV-1 capsid protein used in antiviral research; it disrupts the capsid N-terminal domain (NTD-NTD) interface and exhibits micromolar-range activity.
- Inhibits HIV-1 capsid protein by blocking the NTD-NTD interface.
- Shows micromolar antiviral activity (reported IC50 ≈ 164.2 μM).
- High purity suitable for research applications.
- Available in multiple pack sizes for flexible experimental needs.
- Solid form; soluble in DMSO for solution preparation.
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Medchemexpress LLC 4-Azidobutylamine | 88192-20-5 | 98.0% | 114.15 | 250 MG
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4-Azidobutylamine is a PROTAC linker, characterized by its alkyl chain composition. It is utilized in the synthesis of PROTACs, which are molecules containing two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for a target protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Additionally, it is a click chemistry reagent containing an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PROTAC linker
- Click chemistry reagent
- Contains an Azide group for CuAAc and SPAAC reactions
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Medchemexpress LLC Pyrimidin-4-ylmethanamine | 45588-79-2 | MFCD06796202 | 99.3% | 109.13 g·mol⁻¹ | C5H7N3 | 100 MG
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4-Pyrimidine methanamine (pyrimidin-4-ylmethanamine) is a small-molecule synthetic intermediate used in medicinal chemistry and pharmaceutical synthesis. It features a pyrimidine core with a primary aminomethyl substituent at the 4-position, enabling further derivatization in lead optimization and building-block chemistry.
- High purity for reliable synthesis (Purity (NMR): 99.28%).
- Molecular formula C5H7N3 and molecular weight 109.13 g·mol⁻¹.
- Available in multiple package sizes, including 100 mg to 5 g.
- Suitable as a building block for drug development and synthetic intermediates.
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Medchemexpress LLC Trans-3-(3-pyridyl)acrylic acid | 19337-97-4 | MFCD00006410 | 99.9% | 149.15 g/mol | C8H7NO2 | 5 G
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trans-3-(3-pyridyl)acrylic acid is a trans-3-aryl acrylic acid reported to have antiviral activity against tobacco mosaic virus (TMV). Supplied as a high-purity solid for laboratory research, it is used as a synthetic intermediate and as a biochemical probe in antiviral studies.
- High purity (99.87%) suitable for research applications.
- Well-characterized molecular properties: C8H7NO2, MW 149.15 g/mol.
- Soluble in DMSO at 20 mg/mL; may require ultrasonic agitation.
- Stable solid with defined storage recommendations for powder and solutions.
- Useful as a synthetic intermediate and as a probe for antiviral studies against tobacco mosaic virus (TMV).
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Medchemexpress LLC Allo-aca | 99.82% | 1074.19 | 5 MG
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Allo-aca is a leptin peptidomimetic, acting as a potent and specific leptin receptor antagonist peptide. It effectively blocks leptin signaling and action across various in vitro and in vivo models, demonstrating significant biological activity in cellular and animal studies.
- Inhibits leptin-induced proliferation in MDA-MB-231 cells at 50 pM.
- Inhibits leptin-induced proliferation in MCF-7 cells with an IC50 of 200 pM.
- Reduces VEGF-dependent leptin mRNA expression.
- Inhibits VEGF mitogenic effects.
- Inhibits VEGF-induced chemotaxis and chemokinesis in RF/6A retinal endothelial cells.
- Significantly extends average survival time in an MDA-MB-231 orthotopic mouse xenograft model with subcutaneous administration.
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Medchemexpress LLC Thiamine pyrophosphate (Standard) | 154-87-0 | 98.4% | 460.77 | 100 MG
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Thiamine pyrophosphate (Standard) is the analytical standard of Thiamine pyrophosphate, intended for research and analytical applications. It is the coenzyme form of Vitamin B1 and a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases.
- Analytical standard of thiamine pyrophosphate
- Intended for research and analytical applications
- Coenzyme form of vitamin B1
- Required intermediate in pyruvate dehydrogenase complex and ketoglutarate dehydrogenase complex
- Necessary for oxidative phosphorylation and the pentose phosphate pathway
- Acts as a cofactor for α-ketoacid dehydrogenases
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
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Medchemexpress LLC Methyl methanesulfonate (Standard) | 66-27-3 | 110.13 | 25 G
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Methyl methanesulfonate is an alkylating agent that transfers methyl groups and induces DNA damage. It is a biochemical reagent used as a biological material or organic compound for life science-related research.
- Induces DNA damage
- Transfers methyl groups as an alkylating agent
- Biochemical reagent for life science-related research
- Colorless to light yellow liquid appearance
- Density of 1.3 g/cm³
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Medchemexpress LLC 6-Chloropyrimidine-4-carboxylic acid | 37131-91-2 | 158.54 | 25 G
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6-Chloropyrimidine-4-carboxylic acid is a drug intermediate used for the synthesis of various active compounds. This product is an off-white to yellow solid.
- Drug intermediate for synthesis of various active compounds
- Off-white to yellow solid appearance
- Purity (HPLC) of 98.7%
- 1H NMR spectrum consistent with structure
- Store at -20°C, sealed, away from moisture
- If in solvent, store at -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
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Medchemexpress LLC N2-Methylguanosine | 2140-77-4 | 98.6% | 297.27 | 50 MG
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N2-Methylguanosine is a commonly modified nucleoside found in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. It can also be found in urine and affects the structure and stability of RNA. It can alter the base-pairing behavior of RNA and affect the stability of RNA duplexes and hairpin structures.
- Can form a stable complex with C
- Changes in conformation and stacking may play a crucial role in tRNA recognizing synthetases
- Mechanism of action involves steric hindrance, changes in hydrogen bonds, and alterations in the hydration pattern
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![Medchemexpress LLC 3-[2-(4-hydroxyphenyl)ethyl]phenol | 37116-80-6 | MFCD24713452 | 97.0% | 214.26 g/mol | C14H14O2 | 250MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238951.png-250.jpg)
Medchemexpress LLC 3-[2-(4-hydroxyphenyl)ethyl]phenol | 37116-80-6 | MFCD24713452 | 97.0% | 214.26 g/mol | C14H14O2 | 250MG
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Lunularin is a small-molecule research chemical reported as an 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor and an endogenous metabolite. It is supplied for laboratory and analytical use only. Identifiers: CAS 37116-80-6; formula C14H14O2; molecular weight 214.26 g/mol; listed purity 97.0%.
- Small-molecule 11β-HSD1 inhibitor and endogenous metabolite.
- Intended for research and analytical applications only.
- Purity 97.0% as supplied.
- Molecular weight 214.26 g/mol; formula C14H14O2.
- Available in multiple pack sizes, including a 250 mg pack.
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Medchemexpress LLC Methyl tridecanoate | 1731-88-0 | 228.37 | 5 G
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Methyl tridecanoate moderately inhibits β-amyloid aggregation. It also weakly inhibits acetylcholinesterase (AChE). This product appears as a colorless to light yellow liquid.
- Moderately inhibits β-amyloid aggregation.
- Weakly inhibits acetylcholinesterase (AChE).
- Available in different forms and quantities for research use.
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Medchemexpress LLC Methyl 5-hydroxypyridine-2-carboxylate | 30766-12-2 | 153.14 | 1 ML
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Methyl 5-hydroxypyridine-2-carboxylate | 30766-12-2 | 153.14 | 1 ML
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Medchemexpress LLC Bromindione | 1146-98-1 | 98.1% | 250 MG
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Bromindione is a potent and long-acting, Inandione-derived, oral anticoagulant compound. It is for research use only.
- Potent and long-acting
- Inandione-derived
- Oral anticoagulant compound
- For research use only
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Medchemexpress LLC Sm-360320 (synonym CL-087) | 226907-52-4 | 99.4% | 315.33 g/mol | C15H17N5O3 | 10MG
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SM-360320 is a high-purity small-molecule Toll-like receptor 7 (TLR7) agonist provided for research applications in immunology and cancer-immunotherapy studies. It is supplied in powder and solution formats, with supporting documentation for experimental use. The compound is intended for laboratory research only and is not for clinical use.
- High purity: 99.4% (manufacturer-reported)
- Chemical formula: C15H17N5O3; molecular weight: 315.33 g/mol
- CAS number: 226907-52-4 for unambiguous identification
- Available in multiple pack sizes and as a 10 mM solution in DMSO
- Storage: powder at -20°C; in solvent at -80°C (long-term) or -20°C (short-term)
- Suitable for in vitro and in vivo immunomodulation and screening assays
- Documentation available: datasheet, certificate of analysis, and safety data sheet
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Medchemexpress LLC 17-hydroxyheptadecanoic acid | 13099-34-8 | MFCD00506157 | 99.7% | 286.45 g/mol | C17H34O3 | 250MG
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17-hydroxyheptadecanoic acid is a 17-carbon ω-hydroxy fatty acid supplied as a white to off-white solid intended for research use in lipid metabolism studies and analytical workflows. The material is accompanied by a batch certificate of analysis reporting 99.70% purity (HPLC), and includes molecular formula C17H34O3 and molecular weight 286.45 g/mol. Recommended storage: room temperature for the solid (up to 3 years); in solvent store at -80°C (2 years) or -20°C (1 year).
- High purity suitable for analytical and research applications.
- Batch certificate of analysis available for traceable quality.
- Solid form is convenient for weighing and storage.
- Storage conditions specified for solid and solvent forms.
- Molecular formula and molecular weight provided for method development.
- CAS number 13099-34-8 enables precise identification.
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